Standard

Asthma

KYNU · rs7425446

Where this position leads

Condition: Asthma

rs7425446 Condition: Asthma Asthma Condition rs7425446 rs7425446 KYNU

What the study found

Who was studied 64,538 European ancestry cases, 239,321 European ancestry controls.

The effect Each copy of the A allele carried 1.04 times the odds of Asthma (95% confidence interval 1.02799881345576-1.05908152354951); p = 2 × 10−8.

How common The A allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 2, band 2q22.2 — in an intron of KYNU.

What each result means

A/A Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Asthma. That is a smaller link than two copies.
T/T No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
Source

Questions about rs7425446

What is rs7425446?

rs7425446 is a single position in the genome, in or near the KYNU gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7425446 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs7425446 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7425446 come from?

GWAS Catalog, Nature communications 2020, PMID:32296059. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs7425446). MyGeneLog™. https://www.mygenelog.com/variants/rs7425446

← See all variants