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Lymphocyte count (UKB data field 30120)

OARD1 · rs742495

Where this position leads

Condition: Celiac Disease

rs742495 Condition: Celiac Disease Celiac Disease Condition rs742495 rs742495 OARD1

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0128 higher (95% confidence interval 0.0087-0.017); p = 1 × 10−11.

How common The G allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 6, band 6p21.1 — inside OARD1.

What each result means

A/A No copy of the version the research linked to Lymphocyte count (UKB data field 30120). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Lymphocyte count (UKB data field 30120). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Lymphocyte count (UKB data field 30120). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs742495

What is rs742495?

rs742495 is a single position in the genome, in or near the OARD1 gene. Published research associates it with lymphocyte count (ukb data field 30120). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs742495 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs742495 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs742495 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lymphocyte count (UKB data field 30120) (rs742495). MyGeneLog™. https://www.mygenelog.com/variants/rs742495

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