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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 437 Chinese ancestry cases, 2,551 Chinese ancestry controls; replicated in 195 Chinese ancestry cases, 470 Chinese ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 4 × 10−10.
How common The T allele had a frequency of about 11% in the people studied.
Where it sits Chromosome 2, band 2q24.3 — inside SCN7A.
What each result means
G/GNo copy of the version the research linked to COVID-19 (critical illness vs population). This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to COVID-19 (critical illness vs population). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to COVID-19 (critical illness vs population). That is the strongest link of the three results. A link in a study is not a diagnosis.
Signal transduction and targeted therapy · 2022 · PMID 35368020 · open access
Questions about rs7422259
What is rs7422259?
rs7422259 is a single position in the genome, in or near the SCN7A gene. Published research associates it with covid-19 (critical illness vs population). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7422259 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7422259 come from?
GWAS Catalog, Signal transduction and targeted therapy 2022, PMID:35368020. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
COVID-19 (critical illness vs population) (rs7422259). MyGeneLog™. https://www.mygenelog.com/variants/rs7422259