1 132110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 8,021 European ancestry cases, 16,489 European ancestry controls, 2,495 East Asian ancestry cases, 4,283 East Asian ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.132 higher (95% confidence interval 0.085-0.178); p = 3 × 10−8.
Where it sits Chromosome 6, band 6q21 — in a regulatory region of ATG5.
What each result means
A/ATwo copies of the version the research linked to Primary biliary cholangitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Primary biliary cholangitis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Primary biliary cholangitis. This is the starting point the study compared everyone against.
Journal of hepatology · 2021 · PMID 34033851 · open access
Questions about rs742108
What is rs742108?
rs742108 is a single position in the genome, in or near the ATG5 gene. Published research associates it with primary biliary cholangitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs742108 linked to?
On MyGeneLog this position is linked to Primary Biliary Cholangitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs742108 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs742108 come from?
GWAS Catalog, Journal of hepatology 2021, PMID:34033851. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 132110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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