0 2110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 28,106 European, African, Admixed American, East Asian, South Asian or unknown ancestry individuals (MTAG effective sample size boosted by left ventricular trait samples).
The effect
Each copy of the T allele shifted the measure 0.3 higher (95% confidence interval 0.21-0.39); p = 1 × 10−10.
How common The T allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 1, band 1q32.3 — in an intron of LINC02775.
What each result means
C/CNo copy of the version the research linked to Hypertrophic cardiomyopathy (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Hypertrophic cardiomyopathy (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Hypertrophic cardiomyopathy (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2025 · PMID 39966646 · open access
Questions about rs74139614
What is rs74139614?
rs74139614 is a single position in the genome, in or near the LINC02775 gene. Published research associates it with hypertrophic cardiomyopathy (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs74139614 linked to?
On MyGeneLog this position is linked to Hypertrophic Cardiomyopathy. The research behind each link, and its sources, are set out on that condition page.
Does having rs74139614 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs74139614 come from?
GWAS Catalog, Nature genetics 2025, PMID:39966646. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.