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Dual specificity mitogen-activated protein kinase kinase 2 levels

LAMP1 · rs74115836

What the study found

Who was studied 2,935 Qatari ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.326 higher (95% confidence interval 0.26-0.39); p = 2 × 10−20.

How common The G allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 13, band 13q34 — in an intron of LAMP1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Dual specificity mitogen-activated protein kinase kinase 2 levels — no copies of the reported risk allele.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Dual specificity mitogen-activated protein kinase kinase 2 levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Dual specificity mitogen-activated protein kinase kinase 2 levels compared to the general population.
Source

Questions about rs74115836

What is rs74115836?

rs74115836 is a single position in the genome, in or near the LAMP1 gene. Published research associates it with dual specificity mitogen-activated protein kinase kinase 2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74115836 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74115836 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:36168886. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Dual specificity mitogen-activated protein kinase kinase 2 levels (rs74115836). MyGeneLog™. https://www.mygenelog.com/variants/rs74115836

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