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Who was studied 250 Korean ancestry cases, 296 Korean ancestry controls.
The effect
Each copy of the A allele carried 6.25 times the odds of Intracranial aneurysm (95% confidence interval 3.58-10.9); p = 1 × 10−10.
How common The A allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 13, band 13q34 — in a non-coding transcript of LDHBP1.
What each result means
A/ATwo copies of the version the research linked to Intracranial aneurysm. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Intracranial aneurysm. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Intracranial aneurysm. This is the starting point the study compared everyone against.
Journal of clinical medicine · 2019 · PMID 30823506 · open access
Questions about rs74115822
What is rs74115822?
rs74115822 is a single position in the genome, in or near the CUL4A gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs74115822 linked to?
On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.
Does having rs74115822 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs74115822 come from?
GWAS Catalog, Journal of clinical medicine 2019, PMID:30823506. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 312Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others2Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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