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Neutrophill percentage (UKB data field 30200)

B3GNTL1 · rs7406268

Where this position leads

Condition: Celiac Disease

rs7406268 Condition: Celiac Disease Celiac Disease Condition rs7406268 rs7406268 B3GNTL1

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0151 lower (95% confidence interval 0.011-0.02); p = 1 × 10−11.

How common The A allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 17, band 17q25.3 — in an intron of B3GNTL1.

What each result means

A/A Two copies of the version the research linked to Neutrophill percentage (UKB data field 30200). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Neutrophill percentage (UKB data field 30200). That is a smaller link than two copies.
G/G No copy of the version the research linked to Neutrophill percentage (UKB data field 30200). This is the starting point the study compared everyone against.
Source

Questions about rs7406268

What is rs7406268?

rs7406268 is a single position in the genome, in or near the B3GNTL1 gene. Published research associates it with neutrophill percentage (ukb data field 30200). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7406268 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs7406268 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7406268 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neutrophill percentage (UKB data field 30200) (rs7406268). MyGeneLog™. https://www.mygenelog.com/variants/rs7406268

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