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Male puberty timing (early vs. average onset facial hair)

HERC2 · rs7402990

What the study found

Who was studied 13,226 European ancestry early onset individuals, 161,175 European ancestry average onset individuals.

The effect Each copy of the G allele shifted the measure 0.0185 years lower (95% confidence interval 0.015-0.022); p = 8 × 10−31.

Where it sits Chromosome 15, band 15q13.1 — in an intron of HERC2.

What each result means

A/A No copy of the version the research linked to Male puberty timing (early vs. average onset facial hair). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Male puberty timing (early vs. average onset facial hair). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Male puberty timing (early vs. average onset facial hair). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7402990

What is rs7402990?

rs7402990 is a single position in the genome, in or near the HERC2 gene. Published research associates it with male puberty timing (early vs. average onset facial hair). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7402990 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7402990 come from?

GWAS Catalog, Nature communications 2020, PMID:32210231. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Male puberty timing (early vs. average onset facial hair) (rs7402990). MyGeneLog™. https://www.mygenelog.com/variants/rs7402990

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