Standard

Cerebrospinal fluid t-tau:AB1-42 ratio

LOC105371348 · rs74025622

What the study found

Who was studied 3,146 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 5 × 10−9.

How common The G allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 16, band 16q23.1 — between genes, 104.8 kb from RNA5SP430.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Cerebrospinal fluid t-tau:AB1-42 ratio — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cerebrospinal fluid t-tau:AB1-42 ratio.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cerebrospinal fluid t-tau:AB1-42 ratio compared to the general population.
Source

Questions about rs74025622

What is rs74025622?

rs74025622 is a single position in the genome, in or near the LOC105371348 gene. Published research associates it with cerebrospinal fluid t-tau:ab1-42 ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74025622 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74025622 come from?

GWAS Catalog, Alzheimers Res Ther 2018, PMID:30153862. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cerebrospinal fluid t-tau:AB1-42 ratio (rs74025622). MyGeneLog™. https://www.mygenelog.com/variants/rs74025622

← See all variants