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Who was studied 842 Punjabi Sikh ancestry type 2 diabetes cases, 774 Punjabi Sikh ancestry controls; replicated in 1,108 Punjabi Sikh ancestry type 2 diabetes cases, 1,289 Punjabi Sikh ancestry controls, 2,952 European ancestry myocardial infarction cases and healthy controls, 10,033 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.38 lower (95% confidence interval 0.26-0.50); p = 5 × 10−8.
How common The A allele had a frequency of about 16% in the people studied.
Where it sits Chromosome 16, band 16q21 — in an intron of CSNK2A2.
What each result means
A/ATwo copies of the version the research linked to Telomere length. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Telomere length. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Telomere length. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs74019828
What is rs74019828?
rs74019828 is a single position in the genome, in or near the CSNK2A2 gene. Published research associates it with telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs74019828 linked to?
On MyGeneLog this position is linked to Telomere Length and Epigenetic Age Acceleration. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs74019828?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs74019828 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs74019828 come from?
GWAS Catalog, Circ Cardiovasc Genet 2014, PMID:24795349. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 4632126122126Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others26Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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