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Parental longevity (father's attained age)

SEMA6D · rs74011415

Where this position leads

Condition: Human Lifespan and Longevity

rs74011415 Condition: Human Lifespan and Longevity Human Lifespan and Longevity Condition rs74011415 rs74011415 SEMA6D

What the study found

Who was studied 415,311 British ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0192 lower (95% confidence interval 0.013-0.026); p = 1 × 10−8.

How common The G allele had a frequency of about 88% in the people studied.

Where it sits Chromosome 15, band 15q21.1 — in an intron of SEMA6D.

What each result means

A/A No copy of the version the research linked to Parental longevity (father's attained age). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Parental longevity (father's attained age). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Parental longevity (father's attained age). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs74011415

What is rs74011415?

rs74011415 is a single position in the genome, in or near the SEMA6D gene. Published research associates it with parental longevity (father's attained age). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs74011415 linked to?

On MyGeneLog this position is linked to Human Lifespan and Longevity. The research behind each link, and its sources, are set out on that condition page.

Does having rs74011415 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74011415 come from?

GWAS Catalog, Aging (Albany NY) 2017, PMID:29227965. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Parental longevity (father's attained age) (rs74011415). MyGeneLog™. https://www.mygenelog.com/variants/rs74011415

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