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Lung function (FVC) and body mass index

DIS3L2 · rs73995038

What the study found

Who was studied up to 100,285 Chinese ancestry individuals; replicated in up to 457,756 European ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 4 × 10−16.

Where it sits Chromosome 2, band 2q37.1 — in an intron of DIS3L2.

What each result means

A/A Two copies of the version the research linked to Lung function (FVC) and body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Lung function (FVC) and body mass index. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lung function (FVC) and body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs73995038

What is rs73995038?

rs73995038 is a single position in the genome, in or near the DIS3L2 gene. Published research associates it with lung function (fvc) and body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73995038 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73995038 come from?

GWAS Catalog, The European respiratory journal 2021, PMID:33766948. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lung function (FVC) and body mass index (rs73995038). MyGeneLog™. https://www.mygenelog.com/variants/rs73995038

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