Standard

Mean corpuscular haemoglobin concentration (UKB data field 30060)

near RPH3A · rs739787

Where this position leads

Condition: Celiac Disease

rs739787 Condition: Celiac Disease Celiac Disease Condition rs739787 rs739787 near RPH3A

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0258 lower (95% confidence interval 0.019-0.033); p = 4 × 10−12.

How common The A allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 12, band 12q24.13 — between genes, 26.6 kb from RPH3A.

What each result means

A/A Two copies of the version the research linked to Mean corpuscular haemoglobin concentration (UKB data field 30060). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Mean corpuscular haemoglobin concentration (UKB data field 30060). That is a smaller link than two copies.
G/G No copy of the version the research linked to Mean corpuscular haemoglobin concentration (UKB data field 30060). This is the starting point the study compared everyone against.
Source

Questions about rs739787

What is rs739787?

rs739787 is a single position in the genome, in or near the near RPH3A gene. Published research associates it with mean corpuscular haemoglobin concentration (ukb data field 30060). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs739787 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs739787 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs739787 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular haemoglobin concentration (UKB data field 30060) (rs739787). MyGeneLog™. https://www.mygenelog.com/variants/rs739787

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