Sensitive

Alzheimer's disease or peptic ulcer disease

ZNF232 · rs73976310

Where this position leads

Condition: Alzheimer's Disease

rs73976310 Condition: Alzheimer's Disease Alzheimer's Disease Condition rs73976310 rs73976310 ZNF232

What the study found

Who was studied 71,880 European ancestry Alzheimer's disease or AD-by-proxy cases, 16,666 European ancestry peptic ulcer disease cases, up to 823,039 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−8.

Where it sits Chromosome 17, band 17p13.2 — in an intron of ZNF232.

What each result means

A/A Two copies of the version the research linked to Alzheimer's disease or peptic ulcer disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Alzheimer's disease or peptic ulcer disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Alzheimer's disease or peptic ulcer disease. This is the starting point the study compared everyone against.
Source

Questions about rs73976310

What is rs73976310?

rs73976310 is a single position in the genome, in or near the ZNF232 gene. Published research associates it with alzheimer's disease or peptic ulcer disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73976310 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs73976310 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73976310 come from?

GWAS Catalog, Communications biology 2022, PMID:35851147. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer's disease or peptic ulcer disease (rs73976310). MyGeneLog™. https://www.mygenelog.com/variants/rs73976310

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