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Smoking cessation

near FAM163B · rs739447

What the study found

Who was studied 1,400,535 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0402 higher (95% confidence interval 0.036-0.044); p = 9 × 10−86.

How common The T allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 9, band 9q34.2 — between genes, 3 kb from FAM163B.

What each result means

C/C No copy of the version the research linked to Smoking cessation. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Smoking cessation. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Smoking cessation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs739447

What is rs739447?

rs739447 is a single position in the genome, in or near the near FAM163B gene. Published research associates it with smoking cessation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs739447 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs739447 come from?

GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Smoking cessation (rs739447). MyGeneLog™. https://www.mygenelog.com/variants/rs739447

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