Standard

Nicotine metabolite ratio in current smokers

CYP2G1P · rs73931391

Where this position leads

Condition: Nicotine and Cotinine Metabolism

rs73931391 Condition: Nicotine and Cotinine Metabolism Nicotine and Cotinine Metabolism Condition rs73931391 rs73931391 CYP2G1P

What the study found

Who was studied 437 European ancestry individuals, 364 African American individuals, 453 Latino individuals, 674 Japanese American individuals, 311 Native Hawaiian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.585 lower (95% confidence interval 0.42-0.75); p = 2 × 10−12.

Where it sits Chromosome 19, band 19q13.2 — in an intron of CYP2G1P.

What each result means

A/A No copy of the version the research linked to Nicotine metabolite ratio in current smokers. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Nicotine metabolite ratio in current smokers. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Nicotine metabolite ratio in current smokers. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73931391

What is rs73931391?

rs73931391 is a single position in the genome, in or near the CYP2G1P gene. Published research associates it with nicotine metabolite ratio in current smokers. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73931391 linked to?

On MyGeneLog this position is linked to Nicotine and Cotinine Metabolism. The research behind each link, and its sources, are set out on that condition page.

Does having rs73931391 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73931391 come from?

GWAS Catalog, Cancer Res 2016, PMID:27488534. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Nicotine metabolite ratio in current smokers (rs73931391). MyGeneLog™. https://www.mygenelog.com/variants/rs73931391

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