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Who was studied 425,743 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0262 lower (95% confidence interval 0.021-0.032); p = 9 × 10−20.
How common The A allele had a frequency of about 75% in the people studied.
Where it sits Chromosome 22, band 22q12.2 — in an intron of TBC1D10A.
What each result means
A/ATwo copies of the version the research linked to diastolic blood pressure (DBP, mean, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to diastolic blood pressure (DBP, mean, inv-normal transformed). That is a smaller link than two copies.
C/CNo copy of the version the research linked to diastolic blood pressure (DBP, mean, inv-normal transformed). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs737948
What is rs737948?
rs737948 is a single position in the genome, in or near the TBC1D10A gene. Published research associates it with diastolic blood pressure (dbp, mean, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs737948 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs737948 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs737948 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 131228Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others8Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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