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Who was studied 426,824 British ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0186 higher (95% confidence interval 0.014-0.023); p = 8 × 10−15.
How common The A allele had a frequency of about 81% in the people studied.
Where it sits Chromosome 8, band 8q13.3 — between genes, 21.5 kb from EYA1.
What each result means
A/ATwo copies of the version the research linked to Heel bone mineral density. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Heel bone mineral density. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Heel bone mineral density. This is the starting point the study compared everyone against.
Nature genetics · 2019 · PMID 30598549 · open access
Questions about rs737534
What is rs737534?
rs737534 is a single position in the genome, in or near the EYA1 gene. Published research associates it with heel bone mineral density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs737534 linked to?
On MyGeneLog this position is linked to Heel Bone Mineral Density. The research behind each link, and its sources, are set out on that condition page.
Does having rs737534 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs737534 come from?
GWAS Catalog, Nature genetics 2019, PMID:30598549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1622111Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others11Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Heel bone mineral density (rs737534). MyGeneLog™. https://www.mygenelog.com/variants/rs737534