0 81124Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 740 African American or Afro-Caribbean cases, 120,993 African American or Afro-Caribbean controls, 1,013 European ancestry cases, 449,940 European ancestry controls, 212 Hispanic or Latin American cases, 59,641 Hispanic or Latin American controls.
The effect
Each copy of the T allele shifted the measure 1.8 lower (95% confidence interval 1.74-1.87); p = 1 × 10−11.
How common The T allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 5, band 5p15.31 — between genes, 7.8 kb from MIR4458HG.
What each result means
C/CNo copy of the version the research linked to Systemic lupus erythematosus (PheCode 695.42). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Systemic lupus erythematosus (PheCode 695.42). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Systemic lupus erythematosus (PheCode 695.42). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs73740015
What is rs73740015?
rs73740015 is a single position in the genome, in or near the near MIR4458HG gene. Published research associates it with systemic lupus erythematosus (phecode 695.42). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs73740015 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
Does having rs73740015 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73740015 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 81124Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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