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Platelet-to-lymphocyte ratio

near HLA-B · rs73728881

What the study found

Who was studied 234,552 European ancestry individuals; replicated in 100,478 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 8 × 10−101.

How common The C allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 2.6 kb from HLA-B.

What each result means

C/C Two copies of the version the research linked to Platelet-to-lymphocyte ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Platelet-to-lymphocyte ratio. That is a smaller link than two copies.
T/T No copy of the version the research linked to Platelet-to-lymphocyte ratio. This is the starting point the study compared everyone against.
Source

Questions about rs73728881

What is rs73728881?

rs73728881 is a single position in the genome, in or near the near HLA-B gene. Published research associates it with platelet-to-lymphocyte ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73728881 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73728881 come from?

GWAS Catalog, American journal of human genetics 2021, PMID:34469753. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet-to-lymphocyte ratio (rs73728881). MyGeneLog™. https://www.mygenelog.com/variants/rs73728881

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