0 13211Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others11Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 844 European ancestry individuals (blood measurement), 123 European ancestry individuals (liver measurement), 245 acute lymphoblastic leukemia cases (blood measurement).
The effect
Each copy of the G allele shifted the measure 2.2 lower; p = 1 × 10−72.
How common The G allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 6, band 6p22.3 — between genes, 17.6 kb from NHLRC1.
What each result means
C/CNo copy of the version the research linked to Thiopurine S-methyltransferase activity. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Thiopurine S-methyltransferase activity. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Thiopurine S-methyltransferase activity. That is the strongest link of the three results. A link in a study is not a diagnosis.
Clinical pharmacology and therapeutics · 2017 · PMID 27770449
Questions about rs73726531
What is rs73726531?
rs73726531 is a single position in the genome, in or near the TPMT gene. Published research associates it with thiopurine s-methyltransferase activity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs73726531 affect how medicines work?
TPMT carries pharmacogenomic findings for Thiopurines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs73726531 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73726531 come from?
GWAS Catalog, Clinical pharmacology and therapeutics 2017, PMID:27770449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 13211Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others11Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.