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CLEC4A protein levels

ZNF467 · rs73725601

Where this position leads

Condition: Celiac Disease

rs73725601 Condition: Celiac Disease Celiac Disease Condition rs73725601 rs73725601 ZNF467

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0729 higher (95% confidence interval 0.052-0.094); p = 9 × 10−13.

How common The G allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 7, band 7q36.1 — in an intron of ZNF467.

What each result means

A/A No copy of the version the research linked to CLEC4A protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to CLEC4A protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to CLEC4A protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73725601

What is rs73725601?

rs73725601 is a single position in the genome, in or near the ZNF467 gene. Published research associates it with clec4a protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73725601 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs73725601 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73725601 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CLEC4A protein levels (rs73725601). MyGeneLog™. https://www.mygenelog.com/variants/rs73725601

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