Standard

diastolic blood pressure (DBP, minimum, inv-normal transformed)

near CCN3 · rs73713589

Where this position leads

Condition: Blood Pressure

rs73713589 Condition: Blood Pressure Blood Pressure Condition rs73713589 rs73713589 near CCN3

What the study found

Who was studied 119,331 African American or Afro-Caribbean individuals, 57,991 Hispanic or Latin American individuals, 6,420 East Asian ancestry individuals, 425,735 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0203 higher (95% confidence interval 0.015-0.026); p = 7 × 10−13.

How common The A allele had a frequency of about 80% in the people studied.

Where it sits Chromosome 8, band 8q24.12 — between genes, 20.1 kb from CCN3.

What each result means

A/A Two copies of the version the research linked to diastolic blood pressure (DBP, minimum, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to diastolic blood pressure (DBP, minimum, inv-normal transformed). That is a smaller link than two copies.
G/G No copy of the version the research linked to diastolic blood pressure (DBP, minimum, inv-normal transformed). This is the starting point the study compared everyone against.
Source

Questions about rs73713589

What is rs73713589?

rs73713589 is a single position in the genome, in or near the near CCN3 gene. Published research associates it with diastolic blood pressure (dbp, minimum, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73713589 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs73713589 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73713589 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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diastolic blood pressure (DBP, minimum, inv-normal transformed) (rs73713589). MyGeneLog™. https://www.mygenelog.com/variants/rs73713589

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