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High density lipoprotein cholesterol levels

near CSGALNACT1 · rs73667430

What the study found

Who was studied 313,372 European ancestry individuals, 5,573 African ancestry individuals, 6,689 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0823 lower (95% confidence interval 0.065-0.1); p = 6 × 10−20.

Where it sits Chromosome 8, band 8p21.3 — between genes, 28.9 kb from CSGALNACT1.

What each result means

C/C No copy of the version the research linked to High density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to High density lipoprotein cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to High density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73667430

What is rs73667430?

rs73667430 is a single position in the genome, in or near the near CSGALNACT1 gene. Published research associates it with high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73667430 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73667430 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

High density lipoprotein cholesterol levels (rs73667430). MyGeneLog™. https://www.mygenelog.com/variants/rs73667430

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