Sensitive

Basal cell carcinoma

GATA3 · rs73635312

Where this position leads

Condition: Basal Cell Carcinoma

rs73635312 Condition: Basal Cell Carcinoma Basal Cell Carcinoma Condition rs73635312 rs73635312 GATA3

What the study found

Who was studied 12.945 European ancestry cases, 274,252 European ancestry controls; replicated in 4,242 European ancestry cases, 12,802 European ancestry controls.

The effect Each copy of the G allele carried 1.19 times the odds of Basal cell carcinoma; p = 3 × 10−23.

How common The G allele had a frequency of about 84% in the people studied.

Where it sits Chromosome 10, band 10p14 — in an intron of LINC02676.

What each result means

A/A No copy of the version the research linked to Basal cell carcinoma. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Basal cell carcinoma. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Basal cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73635312

What is rs73635312?

rs73635312 is a single position in the genome, in or near the GATA3 gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73635312 linked to?

On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs73635312 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73635312 come from?

GWAS Catalog, Nat Commun 2016, PMID:27539887. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Basal cell carcinoma (rs73635312). MyGeneLog™. https://www.mygenelog.com/variants/rs73635312

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