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Sleep activity levels

OR4E1 · rs73586669

What the study found

Who was studied 90,515 individuals.

The effect Each copy of the T allele shifted the measure 0.401 lower (95% confidence interval 0.26-0.54); p = 2 × 10−8.

Where it sits Chromosome 14, band 14q11.2 — between genes, 1.9 kb from TRAV24.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Sleep activity levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sleep activity levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sleep activity levels compared to the general population.
Source

Questions about rs73586669

What is rs73586669?

rs73586669 is a single position in the genome, in or near the OR4E1 gene. Published research associates it with sleep activity levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73586669 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73586669 come from?

GWAS Catalog, PLoS Genet 2020, PMID:33075057. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sleep activity levels (rs73586669). MyGeneLog™. https://www.mygenelog.com/variants/rs73586669

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