Sensitive

Endometriosis or depression (pleiotropy)

TYR · rs7358418

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Endometriosis or depression (pleiotropy) — no copies of the reported risk allele. (GWAS Catalog, Hum Genet 2020, PMID:32959083)

G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Endometriosis or depression (pleiotropy). (GWAS Catalog, Hum Genet 2020, PMID:32959083)

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Endometriosis or depression (pleiotropy) compared to the general population. (GWAS Catalog, Hum Genet 2020, PMID:32959083)

Source: GWAS Catalog, Hum Genet 2020, PMID:32959083

Questions about rs7358418

What is rs7358418?

rs7358418 is a single position in the genome, in or near the TYR gene. Published research associates it with endometriosis or depression (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7358418 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7358418 come from?

GWAS Catalog, Hum Genet 2020, PMID:32959083. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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