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Fear of minor pain

LOC105379330 · rs73547001

What the study found

Who was studied Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals.

The effect Each copy of the G allele shifted the measure 3.35 lower (95% confidence interval -); p = 1 × 10−8.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 8, band 8p21.2 — in an intron of LOC105379330.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Fear of minor pain — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Fear of minor pain.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Fear of minor pain compared to the general population.
Source

Questions about rs73547001

What is rs73547001?

rs73547001 is a single position in the genome, in or near the LOC105379330 gene. Published research associates it with fear of minor pain. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73547001 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73547001 come from?

GWAS Catalog, Pain Res Manag 2017, PMID:28701861. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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