near EIF4A1P3 · rs73546868
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 25 cases from twins, 487 controls from twins.
The effect Each copy of the T allele carried 7.90 times the odds of Revision surgery due to aseptic loosening after total knee arthroplasty (95% confidence interval 4.09-15.26); p = 8 × 10−10.
How common The T allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 9, band 9q34.13 — between genes, 30 kb from EIF4A1P3.
rs73546868 is a single position in the genome, in or near the near EIF4A1P3 gene. Published research associates it with revision surgery due to aseptic loosening after total knee arthroplasty. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, The Journal of bone and joint surgery. American volume 2022, PMID:34982741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Revision surgery due to aseptic loosening after total knee arthroplasty (rs73546868). MyGeneLog™. https://www.mygenelog.com/variants/rs73546868