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Pre-treatment viral load in HIV-1 infection

ABTB2 · rs73495598

What the study found

Who was studied 1,398 European ancestry individuals, 572 Black individuals, 418 Hispanic individuals, 13 Asian ancestry individuals, 39 individuals.

The effect Each copy of the T allele shifted the measure 0.4 lower (95% confidence interval 0.32-0.48); p = 5 × 10−21.

How common The T allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 11, band 11p13 — in an intron of ABTB2.

What each result means

C/C No copy of the version the research linked to Pre-treatment viral load in HIV-1 infection. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Pre-treatment viral load in HIV-1 infection. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Pre-treatment viral load in HIV-1 infection. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73495598

What is rs73495598?

rs73495598 is a single position in the genome, in or near the ABTB2 gene. Published research associates it with pre-treatment viral load in hiv-1 infection. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73495598 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73495598 come from?

GWAS Catalog, The Journal of infectious diseases 2019, PMID:31219150. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Pre-treatment viral load in HIV-1 infection (rs73495598). MyGeneLog™. https://www.mygenelog.com/variants/rs73495598

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