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FCN3 protein level (protein group normalized intensity)

near CD164L2 · rs734725

What the study found

Who was studied 1,252 European, Hispanic or African ancestry individuals; replicated in 325 Arab, Indian or Filipino ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.412 lower (95% confidence interval 0.29-0.53); p = 7 × 10−12.

How common The T allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 1, band 1p36.11 — between genes, 0 kb from CD164L2.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of FCN3 protein level (protein group normalized intensity) — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with FCN3 protein level (protein group normalized intensity).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of FCN3 protein level (protein group normalized intensity) compared to the general population.
Source

Questions about rs734725

What is rs734725?

rs734725 is a single position in the genome, in or near the near CD164L2 gene. Published research associates it with fcn3 protein level (protein group normalized intensity). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs734725 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs734725 come from?

GWAS Catalog, Nature genetics 2025, PMID:41310232. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

FCN3 protein level (protein group normalized intensity) (rs734725). MyGeneLog™. https://www.mygenelog.com/variants/rs734725

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