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Who was studied 278 African American or Afro-Caribbean cases, 55,227 African American or Afro-Caribbean controls, 4,047 European ancestry cases, 311,621 European ancestry controls, 235 Hispanic or Latin American cases, 29,079 Hispanic or Latin American controls.
The effect
Each copy of the G allele shifted the measure 3.1 lower (95% confidence interval 3.07-3.12); p = 2 × 10−11.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 18, band 18p11.21 — in the 3′ untranslated region of LDLRAD4.
What each result means
A/ANo copy of the version the research linked to Parkinson's disease. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Parkinson's disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Parkinson's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs73415968
What is rs73415968?
rs73415968 is a single position in the genome, in or near the LDLRAD4 gene. Published research associates it with parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs73415968 linked to?
On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs73415968 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73415968 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 7124Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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