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Urinary albumin-to-creatinine ratio

HBG2 · rs73404549

What the study found

Who was studied 17,664 Sub-Saharan African ancestry, African American or Afro-Caribbean, African ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.2 higher (95% confidence interval 0.12-0.28); p = 8 × 10−13.

How common The T allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 11, band 11p15.4 — in an intron of HBG2.

What each result means

C/C No copy of the version the research linked to Urinary albumin-to-creatinine ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Urinary albumin-to-creatinine ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Urinary albumin-to-creatinine ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73404549

What is rs73404549?

rs73404549 is a single position in the genome, in or near the HBG2 gene. Published research associates it with urinary albumin-to-creatinine ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73404549 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73404549 come from?

GWAS Catalog, Frontiers in genetics 2024, PMID:38812969. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urinary albumin-to-creatinine ratio (rs73404549). MyGeneLog™. https://www.mygenelog.com/variants/rs73404549

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