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Who was studied 38,000 South Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.397 lower (95% confidence interval 0.35-0.45); p = 1 × 10−56.
Where it sits Chromosome 11, band 11p15.4 — in an intron of HBG2.
What each result means
A/ANo copy of the version the research linked to Hemoglobin levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Hemoglobin levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39414775 · open access
Questions about rs73404531
What is rs73404531?
rs73404531 is a single position in the genome, in or near the HBG2 gene. Published research associates it with hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs73404531 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs73404531 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73404531 come from?
GWAS Catalog, Nature communications 2024, PMID:39414775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1722112Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others12Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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