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Serum levels of protein TIMP2

TIMP2 · rs73395197

What the study found

Who was studied 5,341 Icelandic ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.171 lower (95% confidence interval 0.12-0.23); p = 8 × 10−10.

How common The C allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 17, band 17q25.3 — in a non-coding transcript of TIMP2.

What each result means

C/C Two copies of the version the research linked to Serum levels of protein TIMP2. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Serum levels of protein TIMP2. That is a smaller link than two copies.
T/T No copy of the version the research linked to Serum levels of protein TIMP2. This is the starting point the study compared everyone against.
Source

Questions about rs73395197

What is rs73395197?

rs73395197 is a single position in the genome, in or near the TIMP2 gene. Published research associates it with serum levels of protein timp2. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73395197 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73395197 come from?

GWAS Catalog, Nature communications 2022, PMID:35078996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum levels of protein TIMP2 (rs73395197). MyGeneLog™. https://www.mygenelog.com/variants/rs73395197

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