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Systemic lupus erythematosus

NCF1 · rs73366469

Where this position leads

Condition: Systemic Lupus Erythematosus

rs73366469 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs73366469 rs73366469 NCF1

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Systemic lupus erythematosus compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Systemic lupus erythematosus.
T/T Published research associates this genotype with typical/baseline likelihood of Systemic lupus erythematosus — no copies of the reported risk allele.
Source
Genome-wide association study on Northern Chinese identifies KLF2, DOT1L and STAB2 associated with systemic lupus erythematosus
Song Q, Lei Y, Shao L, Li W, Kong Q, Lin Z, Qin X, Wei W, Hou F, Li J, Guo X, Mao Y
and 13 more — show all
Cao Y, Liu Z, Zheng L, Liang R, Jiang Y, Liu Y, Zhang L, Yang J, Lau YL, Zhang Y, Ban B, Wang YF, Yang W
Rheumatology (Oxford, England) · 2021 · PMID 33493351

What people read about alongside this

Infection and immunity2

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs73366469

What is rs73366469?

rs73366469 is a single position in the genome, in or near the NCF1 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73366469 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs73366469?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs73366469 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73366469 come from?

GWAS Catalog, Rheumatology (Oxford) 2021, PMID:33493351. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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