Sensitive

Basal cell carcinoma

UBAC2 · rs7335046

Where this position leads

Condition: Basal Cell Carcinoma

rs7335046 Condition: Basal Cell Carcinoma Basal Cell Carcinoma Condition rs7335046 rs7335046 UBAC2

What the study found

Who was studied 2,045 European ancestry cases, 6,013 European ancestry controls; replicated in 1,426 cases, 4,845 controls.

The effect Each copy of the G allele carried 1.26 times the odds of Basal cell carcinoma (95% confidence interval 1.18-1.34); p = 3 × 10−8.

How common The G allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 13, band 13q32.3 — between genes, 3 kb from UBAC2.

What each result means

C/C No copy of the version the research linked to Basal cell carcinoma. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Basal cell carcinoma. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Basal cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7335046

What is rs7335046?

rs7335046 is a single position in the genome, in or near the UBAC2 gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7335046 linked to?

On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs7335046 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7335046 come from?

GWAS Catalog, Hum Mol Genet 2011, PMID:21700618. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Basal cell carcinoma (rs7335046). MyGeneLog™. https://www.mygenelog.com/variants/rs7335046

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