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Mean platelet volume

PECAM1 · rs73345162

What the study found

Who was studied 7,440 African American individuals, 5,466 Hispanic or Latin American individuals, 10,120 European ancestry individuals, 447 East Asian ancestry individuals, 12 individuals; replicated in 7,857 African ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.15 lower (95% confidence interval 0.11-0.19); p = 5 × 10−10.

How common The C allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 17, band 17q23.3 — in a non-coding transcript of PECAM1.

What each result means

C/C Two copies of the version the research linked to Mean platelet volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean platelet volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean platelet volume. This is the starting point the study compared everyone against.
Source

Questions about rs73345162

What is rs73345162?

rs73345162 is a single position in the genome, in or near the PECAM1 gene. Published research associates it with mean platelet volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73345162 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73345162 come from?

GWAS Catalog, Human molecular genetics 2022, PMID:34553764. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean platelet volume (rs73345162). MyGeneLog™. https://www.mygenelog.com/variants/rs73345162

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