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Serum uromodulin levels (antibody-based assay)

near GNGT2 · rs73338360

What the study found

Who was studied 11,369 European ancestry individuals, 400 African American individuals, 2,216 Hispanic individuals.

The effect Each copy of the C allele shifted the measure 0.242 higher (95% confidence interval 0.19-0.29); p = 5 × 10−24.

How common The C allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 17, band 17q21.32 — between genes, 8.9 kb from GNGT2.

What each result means

C/C Two copies of the version the research linked to Serum uromodulin levels (antibody-based assay). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Serum uromodulin levels (antibody-based assay). That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum uromodulin levels (antibody-based assay). This is the starting point the study compared everyone against.
Source

Questions about rs73338360

What is rs73338360?

rs73338360 is a single position in the genome, in or near the near GNGT2 gene. Published research associates it with serum uromodulin levels (antibody-based assay). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73338360 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73338360 come from?

GWAS Catalog, JCI insight 2022, PMID:35446786. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum uromodulin levels (antibody-based assay) (rs73338360). MyGeneLog™. https://www.mygenelog.com/variants/rs73338360

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