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Lifetime smoking index

CLYBL · rs7333559

What the study found

Who was studied 462,690 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.015 higher (95% confidence interval 0.011-0.019); p = 3 × 10−10.

How common The G allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 13, band 13q32.3 — in the 3′ untranslated region of CLYBL.

What each result means

A/A No copy of the version the research linked to Lifetime smoking index. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Lifetime smoking index. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Lifetime smoking index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7333559

What is rs7333559?

rs7333559 is a single position in the genome, in or near the CLYBL gene. Published research associates it with lifetime smoking index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7333559 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7333559 come from?

GWAS Catalog, Psychological medicine 2020, PMID:31689377. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lifetime smoking index (rs7333559). MyGeneLog™. https://www.mygenelog.com/variants/rs7333559

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