Standard
Pneumoconiosis in silica exposure
MDM2 · rs73329476
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Pneumoconiosis in silica exposure — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Pneumoconiosis in silica exposure.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Pneumoconiosis in silica exposure compared to the general population.
Source
A genome-wide association study identifies susceptibility loci of silica-related pneumoconiosis in Han Chinese
Chu M,
Ji X,
Chen W,
Zhang R,
Sun C,
Wang T,
Luo C,
Gong J,
Zhu M,
Fan J,
Hou Z,
Dai J
and 6 more — show all
Human molecular genetics · 2014 · PMID 24986923
Questions about rs73329476
What is rs73329476?
rs73329476 is a single position in the genome, in or near the MDM2 gene. Published research associates it with pneumoconiosis in silica exposure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs73329476 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73329476 come from?
GWAS Catalog, Hum Mol Genet 2014, PMID:24986923. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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