Sensitive

Systemic lupus erythematosus

ELF1 · rs7329174

Where this position leads

Condition: Systemic Lupus Erythematosus

rs7329174 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs7329174 rs7329174 ELF1

What the study found

Who was studied 612 Chinese ancestry cases, 1,160 Chinese ancestry controls; replicated in 2,090 Chinese ancestry cases, 1,981 Chinese ancestry controls, 462 Thai ancestry cases, 951 Thai ancestry controls.

The effect Each copy of the G allele carried 1.26 times the odds of Systemic lupus erythematosus (95% confidence interval 1.16-1.36); p = 1 × 10−8.

How common The G allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 13, band 13q14.11 — in an intron of ELF1.

What each result means

A/A No copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7329174

What is rs7329174?

rs7329174 is a single position in the genome, in or near the ELF1 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7329174 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

Does having rs7329174 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7329174 come from?

GWAS Catalog, Hum Mol Genet 2010, PMID:21044949. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systemic lupus erythematosus (rs7329174). MyGeneLog™. https://www.mygenelog.com/variants/rs7329174

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