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Who was studied 153,950 Korean ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0982 higher (95% confidence interval 0.085-0.112); p = 2 × 10−46.
How common The C allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 10, band 10q11.22 — between genes, 7.8 kb from ZFAND4.
What each result means
A/ANo copy of the version the research linked to Mean corpuscular volume. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Mean corpuscular volume. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Mean corpuscular volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2025 · PMID 40436827 · open access
Questions about rs73291195
What is rs73291195?
rs73291195 is a single position in the genome, in or near the near ZFAND4 gene. Published research associates it with mean corpuscular volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs73291195 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs73291195 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73291195 come from?
GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Mean corpuscular volume (rs73291195). MyGeneLog™. https://www.mygenelog.com/variants/rs73291195