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RGMA protein levels

LINC00393 · rs7328187

Where this position leads

Condition: Celiac Disease

rs7328187 Condition: Celiac Disease Celiac Disease Condition rs7328187 rs7328187 LINC00393

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0394 higher (95% confidence interval 0.029-0.05); p = 2 × 10−18.

How common The G allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 13, band 13q22.1 — in an intron of LINC00393.

What each result means

G/G Two copies of the version the research linked to RGMA protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to RGMA protein levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to RGMA protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs7328187

What is rs7328187?

rs7328187 is a single position in the genome, in or near the LINC00393 gene. Published research associates it with rgma protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7328187 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs7328187 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7328187 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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RGMA protein levels (rs7328187). MyGeneLog™. https://www.mygenelog.com/variants/rs7328187

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