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Mean corpuscular haemoglobin (UKB data field 30050)

FOXO1 · rs7323267

Where this position leads

Condition: Celiac Disease

rs7323267 Condition: Celiac Disease Celiac Disease Condition rs7323267 rs7323267 FOXO1

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0248 lower (95% confidence interval 0.02-0.029); p = 5 × 10−30.

How common The C allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 13, band 13q14.11 — in an intron of FOXO1.

What each result means

C/C Two copies of the version the research linked to Mean corpuscular haemoglobin (UKB data field 30050). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean corpuscular haemoglobin (UKB data field 30050). That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean corpuscular haemoglobin (UKB data field 30050). This is the starting point the study compared everyone against.
Source

Questions about rs7323267

What is rs7323267?

rs7323267 is a single position in the genome, in or near the FOXO1 gene. Published research associates it with mean corpuscular haemoglobin (ukb data field 30050). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7323267 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs7323267 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7323267 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular haemoglobin (UKB data field 30050) (rs7323267). MyGeneLog™. https://www.mygenelog.com/variants/rs7323267

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