Sensitive

Epigenetic age acceleration (Horvath) in childhood cancer survivors

SELP · rs732314

What the study found

Who was studied 2,640 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.57 higher (95% confidence interval 0.39-0.75); p = 3 × 10−11.

Where it sits Chromosome 1, band 1q24.2 — in an intron of SELP.

What each result means

C/C Two copies of the version the research linked to Epigenetic age acceleration (Horvath) in childhood cancer survivors. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Epigenetic age acceleration (Horvath) in childhood cancer survivors. That is a smaller link than two copies.
T/T No copy of the version the research linked to Epigenetic age acceleration (Horvath) in childhood cancer survivors. This is the starting point the study compared everyone against.
Source

Questions about rs732314

What is rs732314?

rs732314 is a single position in the genome, in or near the SELP gene. Published research associates it with epigenetic age acceleration (horvath) in childhood cancer survivors. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs732314 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs732314 come from?

GWAS Catalog, Genome medicine 2022, PMID:35313970. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Epigenetic age acceleration (Horvath) in childhood cancer survivors (rs732314). MyGeneLog™. https://www.mygenelog.com/variants/rs732314

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