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Who was studied 446,118 European ancestry individuals; replicated in 47,180 adults, 10,554 children or adolescents.
The effect
Each copy of the G allele shifted the measure 0.906 higher; p = 5 × 10−11.
Where it sits Chromosome 8, band 8p22 — in an intron of SGCZ.
What each result means
A/ANo copy of the version the research linked to Sleep duration. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Sleep duration. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Sleep duration. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 30846698 · open access
Questions about rs73219758
What is rs73219758?
rs73219758 is a single position in the genome, in or near the SGCZ gene. Published research associates it with sleep duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs73219758 linked to?
On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.
Does having rs73219758 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73219758 come from?
GWAS Catalog, Nature communications 2019, PMID:30846698. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 927Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others7Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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