Standard

Aspartate aminotransferase to alanine aminotransferase ratio

near SCAF4 · rs73201559

Where this position leads

Condition: Gout

rs73201559 Condition: Gout Gout Condition rs73201559 rs73201559 near SCAF4

What the study found

Who was studied 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0359 higher (95% confidence interval 0.024-0.047); p = 1 × 10−9.

Where it sits Chromosome 21, band 21q22.11 — between genes, 14.4 kb from SCAF4.

What each result means

C/C No copy of the version the research linked to Aspartate aminotransferase to alanine aminotransferase ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Aspartate aminotransferase to alanine aminotransferase ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Aspartate aminotransferase to alanine aminotransferase ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73201559

What is rs73201559?

rs73201559 is a single position in the genome, in or near the near SCAF4 gene. Published research associates it with aspartate aminotransferase to alanine aminotransferase ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73201559 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs73201559 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73201559 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Aspartate aminotransferase to alanine aminotransferase ratio (rs73201559). MyGeneLog™. https://www.mygenelog.com/variants/rs73201559

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