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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 10,217 European ancestry individuals, 5,717 individuals.
The effect
Each copy of the C allele shifted the measure 0.11 lower (95% confidence interval 0.077-0.143); p = 3 × 10−10.
How common The C allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 21, band 21q22.12 — in an intron of RUNX1.
What each result means
C/CTwo copies of the version the research linked to Hip shape (DXA scan). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Hip shape (DXA scan). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Hip shape (DXA scan). This is the starting point the study compared everyone against.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019 · PMID 30320955 · open access
Questions about rs73197346
What is rs73197346?
rs73197346 is a single position in the genome, in or near the RUNX1 gene. Published research associates it with hip shape (dxa scan). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs73197346 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73197346 come from?
GWAS Catalog, J Bone Miner Res 2018, PMID:30320955. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Hip shape (DXA scan) (rs73197346). MyGeneLog™. https://www.mygenelog.com/variants/rs73197346